Each tablet contains Glimepiride (Glucoryl-M) 2 mg and Metformin (Glucoryl-M) HCl (in sustained-release form) 500 mg. It also contains the following excipients: Hypromellose, sodium carboxymethyl cellulose, methacrylic acid copolymer dispersion, macrogol, povidone, magnesium stearate, purified water, sodium starch glycolate, lactose, titanium dioxide, microcrystalline cellulose, magnesium stearate and pregelatinized starch. Colors: Yellow ferric oxide and titanium dioxide.

Some diabetic patients taking Glucoryl M 1 Tablet 15's may develop a rare but serious condition called lactic acidosis. In this condition, there is too much lactic acid accumulated in the blood. So, your liver and kidney proper functioning is required for the elimination of excess lactic acid from the blood. You should not take Glucoryl M 1 Tablet 15's if you have kidney disease, as measured by a blood test. Glucoryl M 1 Tablet 15's may lower vitamin B12 levels, so try to have blood test annual blood and vitamin. Glucoryl M 1 Tablet 15's when used with or without insulin has the tendency to extremely lower the blood sugar level. So, the doctor may lower the dose of insulin. Glucoryl M 1 Tablet 15's may lower your thyroid-stimulating hormone (TSH), so an annual check-up of TSH is suggested.