Each tablet contains Glimepiride Glucoryl M 2 mg and Metformin Glucoryl M HCl in sustained release form 500 mg It also contains the following excipients Hypromellose sodium carboxymethyl cellulose methacrylic acid copolymer dispersion macrogol povidone magnesium stearate purified water sodium starch glycolate lactose titanium dioxide microcrystalline cellulose magnesium stearate and pregelatinized starch Colors Yellow ferric oxide and titanium dioxide

Some diabetic patients taking Glucoryl M 1 Tablet 15 s may develop a rare but serious condition called lactic acidosis In this condition there is too much lactic acid accumulated in the blood So your liver and kidney proper functioning is required for the elimination of excess lactic acid from the blood You should not take Glucoryl M 1 Tablet 15 s if you have kidney disease as measured by a blood test Glucoryl M 1 Tablet 15 s may lower vitamin B12 levels so try to have blood test annual blood and vitamin Glucoryl M 1 Tablet 15 s when used with or without insulin has the tendency to extremely lower the blood sugar level So the doctor may lower the dose of insulin Glucoryl M 1 Tablet 15 s may lower your thyroid stimulating hormone TSH so an annual check up of TSH is suggested