Xirtam H Tablet 10 s belongs to a group of medications called anti hypertensives primarily used for lowering high blood pressure hypertension by removing extra fluid electrolytes from the body High blood pressure is a chronic condition in which the blood s force against the artery wall is high As a result it increases the risk of heart related diseases like heart attack heart failure stroke irregular heartbeat and other complications Xirtam H Tablet 10 s is a combination of two medicines namely Olmesartan medoximil and Hydrochlorothiazide Olmesartan medoximil is a prodrug and breaks down into Active form i e olmesartan once absorbed in the GIT Gastrointestinal tract It is an angiotensin receptor blocker ARB that blocks the hormone angiotensin thereby relaxing and widening the narrowed blood vessels This allows the blood to flow more smoothly in the blood vessels and the heart can pump more efficiently On the other hand Hydrochlorothiazide is a diuretic or water pill that works by removing extra water fluid and certain electrolytes overload from the body Together Xirtam H Tablet 10 s lowers the fluid overload raised blood pressure improves blood flow and reduce the future risk of a heart attack and stroke