Venpres-H 40mg/12.5mg Tablet contains two medicines, both of which help to control high blood pressure. It is generally used when one medicine alone is not controlling the blood pressure effectively. Lowering blood pressure helps to reduce your risk of having a heart attack or a stroke in the future. You can take Venpres-H 40mg/12.5mg Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It’s important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more, so it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly even if you feel better to get the most from it. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.