Stratum corneum is the surface layer of the epidermis. Water content of Stratum corneum (10%) is controlling factor in maintaining skin flexibility. When water content falls below 10%, Stratum corneum becomes less flexible and rough. This phenomenon is termed as ‘dry skin’. Certain skin disorders and systemic diseases also produce dry skin. Moyzen produces thin occlusive film on the Stratum corneum, which prevents loss of moisture from skin surface.