Description:
Clarinathromycin (Pylokit) and other macrolides bind reversibly to the 50S subunit of the ribosome, resulting in blockage of the transpeptidation or translocation reactions, inhibition of protein synthesis, and hence inhibition of cell growth. Its action is predominantly bacteriostatic, but high concentrations are slowly bactericidal against the more sensitive strains. Because macrolides penetrate readily into white blood cells and macrophages, there has been some interest in their potential synergy with the host defense mechanism in vivo.
Uses / Indications:
Pregnidoxin Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
Vomiting
Emesis
Biliousness
Dizziness
Bronchopulmonary dysplasia in premature infants
Vomit
Convulsions
Dizzines
Drowsiness
Cerebral palsy
Side Effects:
Signs of an allergic reaction to Clarinathromycin (Pylokit): hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
headache with chest pain and severe dizziness, fast or pounding heartbeats, shortness of breath, fainting,
diarrhea that is watery or bloody,
fever, swollen glands, body aches, flu symptoms, new or worsening cough,
skin rash, easy bruising or bleeding, severe tingling, numbness, pain, muscle weakness,
problems with your hearing,
signs of a kidney problem--little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Older adults may be more likely to have heart rhythm side effects, including a life-threatening fast heart rate.
Clarinathromycin (Pylokit) may also cause severe liver symptoms. Stop taking Clarinathromycin (Pylokit) and call your doctor at once if you have any of these liver symptoms:
itching, tired feeling,
Nausea, upper stomach pain, loss of appetite,
dark urine, clay colored stools or
jaundice (yellowing of the skin or eyes).
Common Clarinathromycin (Pylokit) side effects may include:
stomach pain, indigestion, gas,
vomiting, mild diarrhea,
unusual or unpleasant taste in your mouth,
headache, sleep problems (insomnia),
mild itching or rash or
vaginal itching or discharge.
Medicine interaction:
If you use other drugs or over the counter products at the same time, the effects of Pregnidoxin Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Pregnidoxin Tablet may interact with the following drugs and products:
Alcohol
Atropine
Cimetidine
Disulfiram
Ephedrine
Fluoroquinolones
Mexiletine
Oral contraceptives
