Endoxan is used to treat cancer of the ovaries, breast, blood and lymph system, and nerves (mainly in children). Endoxan is also used for retinoblastoma (a type of eye cancer mainly in children), multiple myeloma (cancer in the bone marrow), and mycosis fungoides (tumors on the skin). It belongs to the group of cancer medicines called alkylating agents. Endoxan is also used for some kinds of kidney disease. Endoxan interferes with the growth of cancer cells, which are then destroyed by the body. Since the growth of normal body cells may also be affected by Endoxan, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used. Before you begin treatment with Endoxan, you and your doctor should talk about the benefits of Endoxan as well as the risks of using it. Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Endoxan is used in certain patients with the following medical conditions: Cancer of the adrenal cortex (the outside layer of the adrenal gland). Cancer of the bladder. Cancer in the bones. Cancer of the cervix. Cancer of the endometrium. Cancers of the lungs. Cancer of the prostate. Cancer of the testicles. Ewing's sarcoma (a certain type of bone cancer). Germ cell tumors in the ovaries (a cancer in the egg-making cells in the ovary). Gestational trophoblastic tumors (a certain type of tumor in the uterus/womb). Histiocytosis X (a type of cancer found mainly in children). Organ transplant rejection (prevention). Rheumatoid arthritis. Soft tissue sarcomas (a cancer of the muscles, tendons, vessels that carry blood or lymph, joints, and fat). Systemic dermatomyositis. Systemic lupus erythematosus. Thymoma (a cancer in the thymus, a small organ beneath the breastbone). Tumors in the brain Waldenström's macroglobulinemia (a certain type of cancer of the blood). Wegener's granulomatosis. Wilms' tumor (a cancer of the kidney found primarily in children).

Do not take Endoxan Tablet 10's if you are allergic to any of its contents; if you have urinary flow obstruction, bone marrow suppression, or any infections. Talk to your doctor before taking Endoxan Tablet 10's if you have myelosuppression, immunosuppression, infections, diabetes, heart, lung, liver, or kidney problems. Inform your doctor if you are receiving any radiotherapy or chemotherapy. Avoid taking Endoxan Tablet 10's if you are pregnant or breastfeeding. Endoxan Tablet 10's may cause dizziness, so drive only if you are alert. Endoxan Tablet 10's should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Endoxan Tablet 10's as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Endoxan Tablet 10's to rule out any side effects.