Combither Forte 80 mg/480 mg Tablet is used for the treatment of malaria in both children and adults. It contains two medicines both of which belong to a group of medicines called antimalarials. However, it is not used to prevent malaria or to treat severe/complicated malaria (when the brain, lungs, or kidneys are affected). Combither Forte 80 mg/480 mg Tablet works by killing the malaria-causing parasites thereby preventing further spread of the infection. It should be taken with food as this will help your body better absorb the medicine. Take it in the dose and duration advised by your doctor. Do not take more than the recommended dose, as this may have harmful effects on your body. Complete the full course of treatment to make sure the infection is treated completely.