CIRROSAM contains S-Adenosyl L-Methionine (Ademetionine) which has a place with the class of prescriptions called nutraceutical specialists. It is demonstrated for the treatment of intrahepatic cholestasis in grown-up patients with liver illness. Intrahepatic cholestasis is a cholestatic problem portrayed by diminished progression of bile from the liver. It tends to be caused because of any fundamental liver circumstances, for example, alcoholic liver sickness, liver cirrhosis, hepatitis, nerve stones or hepatocellular carcinoma. Side effects incorporates serious tingling, yellowing of skin or eyes, sickness, loss of hunger, dim pee and light-shaded defecation. CIRROSAM can likewise be utilized to treat intrahepatic cholestasis of pregnancy (tingling and raised degrees of serum aminotransferases and bile corrosive during second or third trimester). S-Adenosyl L-Methionine is regular substance present in the body. It is a subsidiary of amino corrosive called methionine and is answerable for different liver capacities, hepatocyte development and separation. Supplementation of s-adenosyl l-methionine in liver illness patients diminishes oxidative pressure, irritation and offers assurance against apoptotic cell passing and ensuing fibrosis.