Description:
Progestins are hormones. They are used by both men and women for different purposes.
Progestins are prescribed for several reasons:
To properly regulate the menstrual cycle and treat unusual stopping of the menstrual periods (amenorrhea). Progestins work by causing changes in the uterus. After the amount of progestins in the blood drops, the lining of the uterus begins to come off and vaginal bleeding occurs (menstrual period). Progestins help other hormones start and stop the menstrual cycle.
To help a pregnancy occur during egg donor or infertility procedures in women who do not produce enough Susten. Also, Susten is given to help maintain a pregnancy when not enough of it is made by the body.
To prevent estrogen from thickening the lining of the uterus (endometrial hyperplasia) in women around menopause who are being treated with estrogen for ovarian hormone therapy (OHT). OHT is also called hormone replacement therapy (HRT) and estrogen replacement therapy (ERT).
To treat pain that is related to endometriosis, a condition where the endometrial tissue which lines the uterus becomes displaced in other female organs.
To treat a condition called endometriosis, to help prevent endometrial hyperplasia, or to treat unusual and heavy bleeding of the uterus (dysfunctional uterine bleeding) by starting or stopping the menstrual cycle.
To help treat cancer of the breast, kidney, or uterus. Progestins help change the cancer cell's ability to react to other hormones and proteins that cause tumor growth. In this way, progestins can stop the growth of a tumor.
To test the body's production of certain hormones such as estrogen.
To treat loss of appetite and severe weight or muscle loss in patients with acquired immunodeficiency syndrome (AIDS) or cancer by causing certain proteins to be produced that cause increased appetite and weight gain.
Progestins may also be used for other conditions as determined by your doctor.
Depending on how much and which Susten you use or take, a Susten can have different effects. For instance, high doses of Susten are necessary for some women to continue a pregnancy while other progestins in low doses can prevent a pregnancy from occurring. Other effects include causing weight gain, increasing body temperature, developing the milk-producing glands for breast-feeding, and relaxing the uterus to maintain a pregnancy.
Progestins can help other hormones work properly. Progestins may help to prevent anemia (low iron in blood), too much menstrual blood loss, and cancer of the uterus.
Progestins are available only with your doctor's prescription.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, progestins are used in certain patients with the following medical conditions:
Carcinoma of the prostate
Corpus luteum insufficiency
Hot flashes
Polycystic ovary syndrome
Precocious puberty
Uses / Indications:
Susten 100 Soft Gelatin Capsule is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
Recurrent miscarriage
Absence of a menstrual period
Uterine bleeding
Side Effects:
Along with their needed effects, progestins used in high doses sometimes cause some unwanted effects such as blood clots, heart attacks, and strokes, or problems of the liver and eyes. Although these effects are rare, some of them can be very serious and cause death. It is not clear if these problems are due to the Susten. They may be caused by the disease or condition for which progestins are being used.
The following side effects may be caused by blood clots. Although not all of these side effects may occur, if they do occur they need immediate medical attention.
Get emergency help immediately if any of the following side effects occur:
Rare
Symptoms of blood clotting problems, usually severe or sudden, such as:
headache or migraine
loss of or change in speech, coordination, or vision
numbness of or pain in chest, arm, or leg
unexplained shortness of breath
Check with your doctor as soon as possible if any of the following side effects occur:
More common
Changes in vaginal bleeding (increased amounts of menstrual bleeding occurring at regular monthly periods, lighter vaginal bleeding between menstrual periods, heavier vaginal bleeding between regular monthly periods, or stopping of menstrual periods)
symptoms of blood sugar problems (dry mouth, frequent urination, loss of appetite, or unusual thirst)
Less common
Mental depression
skin rash
unexpected or increased flow of breast milk
RareFor megestrol—During chronic treatment
Backache
dizziness
filling or rounding out of the face
irritability
mental depression
Nausea or vomiting
unusual decrease in sexual desire or ability in men
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Abdominal pain or cramping
bloating or swelling of ankles or feet
blood pressure increase (mild)
dizziness
drowsiness (Susten only)
headache (mild)
mood changes
nervousness
pain or irritation at place of Injection site
swelling of face, ankles, or feet
unusual or rapid weight gain
Less common
Acne
breast pain or tenderness
brown spots on exposed skin, possibly long-lasting
hot flashes
loss or gain of body, facial, or scalp hair
loss of sexual desire
trouble in sleeping
Not all of the side effects listed above have been reported for each of these medicines, but they have been reported for at least one of them. All of the progestins are similar, so any of the above side effects may occur with any of these medicines.
After you stop using Susten, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this period of time check with your doctor if you notice the following side effect:
For megestrol
Dizziness
Nausea or vomiting
unusual tiredness or weakness
Delayed return to fertility
stopping of menstrual periods
unusual menstrual bleeding (continuing)
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Medicine interaction:
If you use other drugs or over the counter products at the same time, the effects of Susten 100 Soft Gelatin Capsule may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Susten 100 Soft Gelatin Capsule may interact with the following drugs and products:
Carbamazepine
Estradiol
Phenytoin
Rifampin