Obetohep is an agonist for FXR a nuclear receptor expressed in the liver and intestine FXR is a key regulator of bile acid inflammatory fibrotic and metabolic pathways FXR Activation decreases the intracellular hepatocyte concentrations of bile acids by suppressing de novo synthesis from cholesterol as well as by increased transport of bile acids out of the hepatocytes These mechanisms limit the overall size of the circulating bile acid pool while promoting choleresis thus reducing hepatic exposure to bile acids

Do not take Obetohep 5mg Tablet 10 s if you are allergic to any of its contents if you have a complete blockage of the biliary tract liver bile ducts and gall bladder Inform your doctor if you experience itching that is difficult to tolerate Consult your doctor before taking Obetohep 5mg Tablet 10 s if you are pregnant or breastfeeding Obetohep 5mg Tablet 10 s is not recommended for children or adolescents Obetohep 5mg Tablet 10 s may cause dizziness so drive with caution Inform your doctor if you have had cirrhosis of the liver as Obetohep 5mg Tablet 10 s may cause liver damage Consult a doctor immediately if you experience yellowing of the skin eyes black tarry stools dark urine coughing up vomiting blood confusion slurred speech mood swings anxiety swelling in and around the stomach