Enzar-HS (pancrelipase) is a combination of three enzymes (proteins): lipase, protease, and amylase. These enzymes are normally produced by the pancreas and are important in the digestion of fats, proteins, and sugars. Enzar-HS is used to replace these enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, including cystic fibrosis, chronic inflammation of the pancreas, or blockage of the pancreatic ducts. Enzar-HS may also be used following surgical removal of the pancreas.

Do not take Enzar-HS Capsule 10's if you are allergic to pork (pig), cow or buffalo products. Consult your doctor if you experience stomach pain, swelling, constipation, and vomiting as patients taking Enzar-HS Capsule 10's with cystic fibrosis may develop a rare bowel condition called fibrosing colonopathy. Inform your doctor before taking Enzar-HS Capsule 10's if you have gout, asthma, or any disease condition. Consult your doctor before taking Enzar-HS Capsule 10's if you are pregnant or breastfeeding. Enzar-HS Capsule 10's may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with Enzar-HS Capsule 10's; please consult your doctor if you have any concerns regarding this. Enzar-HS Capsule 10's can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight. Enzar-HS Capsule 10's might interfere with the absorption and reduce iron supplements and folic acid, so maintain a minimum gap between both. Enzar-HS Capsule 10's reduces iron absorption (especially on prolonged use). Simultaneous use of antacids containing calcium carbonate and/or magnesium hydroxide may lead to pancreatin deficiency.