Glucoryl M 2 Forte Tablet 15 s is a combination of two anti diabetic drugs Glimepiride and Metformin Glimepiride which is a sulfonylurea acts by increasing the amount of insulin released by the pancreas Metformin which is a biguanide acts by lowering the glucose production in the liver delaying glucose absorption from the intestines and increasing the body s response to insulin In a nutshell the two medicines together prevent the blood glucose levels from rising to very high levels thus keeping your Diabetes under control Type 2 diabetes is a chronic or lifelong condition that affects the way your body processes glucose People with type 2 diabetes either do not produce enough insulin or if at all the insulin is produced it is unable to perform its function in the body insulin resistance Due to this the blood glucose level increases and symptoms such as frequent urination increased thirst and increased hunger start It can lead to serious complications like skin infection eye problems retinopathy nerve damage neuropathy diabetic foot foot ulcer kidney disease nephropathy high blood pressure and even stroke