Gliclazide (Glizid-M) is a sulfonylurea hypoglycemic agent which reduces blood glucose levels in type 2 diabetes mellitus by increasing the release of insulin from pancreatic ß-cells. It primarily enhances the 1st phase of insulin secretion, but also to a degree, its 2nd phase. Both phases are diminished in type 2 diabetes mellitus.

Some diabetic patient taking Glizid-M Tablet 15's may develop a rare but serious condition called lactic acidosis. In this condition, there is too much of lactic acid accumulated in the blood. So, your liver and kidney proper functioning is required for elimination of excess lactic acid from the blood. You should not take Glizid-M Tablet 15's if you have kidney disease, as measured by a blood test. Glizid-M Tablet 15's may lower vitamin B12 levels, so try to have blood test annual blood and vitamin. Glizid-M Tablet 15's, when used with or without insulin, has the tendency to extremely lower the blood sugar level. So, the doctor may lower the dose of insulin. Glizid-M Tablet 15's may lower your thyroid-stimulating hormone (TSH), so annual check-up of TSH is suggested.