Napra D 250 Tablet is a mix of two medications utilized in the prevention of migraines It blocks the release of certain chemical messengers that cause pain inflammation and fever It also blocks the signals in the brain that cause nausea and vomiting associated with migraines Napra D 250 Tablet may be recommended alone or in mix with another medication It can be taken with or without food The dose and duration will depend on the severity of your condition and how well it helps your symptoms Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop Using of the medication may cause few common side effects such as flu like symptoms indigestion and dryness in the mouth If you experience any such side effects that do not go away or get worse you should let your doctor know Your doctor may be able to suggest ways of preventing or reducing the symptoms In general you should try to use the smallest amount necessary to control your symptoms