Dolostat MR 100 mg 325 mg 500 mg Tablet is a mix medication that helps in relieving muscular pain It works by blocking the release of certain chemical messengers that cause pain inflammation and fever This improves the movement of muscles and provides relief from pain and discomfort Dolostat MR 100 mg 325 mg 500 mg Tablet can be taken with or without food The dose and duration will depend on the severity of your condition You should keep taking the medication even if you feel better until the doctor says it is alright to stop using it Using this medication may cause common side effects such as nausea vomiting heartburn stomach pain diarrhea and loss of appetite If these persist or get worse let your doctor know In general you should try to use the smallest amount necessary to control your symptoms