Betamethasone (Betnovate-S) dipropionate, are effective in the treatment of corticosteroid-responsive dermatoses primarily because of their anti-inflammatory, antipruritic and vasoconstrictive actions. While the physiologic, pharmacologic, and clinical effects of the corticosteroids are well known, the exact mechanisms of their actions in each disease are uncertain. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes, by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A.

Do not use Betnovate S Ointment 20 gm in more than prescribed doses, on large areas of the body or for a prolonged time as it may change the levels of some hormones in the body. If you are known to be allergic to Betnovate S Ointment 20 gm or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Betnovate S Ointment 20 gm. Do not wrap or cover the treated area with plasters or bandages. Avoid using Betnovate S Ointment 20 gm for more than 5 days in children and on the face. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Betnovate S Ointment 20 gm catches fire and burns easily. If you have rosacea (redness and often red, small, pus-filled bumps on the face), psoriasis, acne, dermatitis (redness and swelling of the skin) around the mouth, chickenpox, cold sores, nappy rash, genital itching or other skin problems, glaucoma, cataracts, diabetes, adrenal gland, liver or blood circulation problems, inform your doctor before taking Betnovate S Ointment 20 gm. This medicine should not be used in bacterial/fungal infections, or napkin eruptions, without suitable concomitant anti-infective therapy. In rare cases, adrenal hormone suppression may also occur with Betnovate S Ointment 20 gm, especially in infants and children.