It is a more potent statin which competitively inhibits the conversion of 3 hydroxy 3 methyl glutaryl coenzyme A HMG CoA to mevalonate The drug exerts it s action by specific inhibition of enzyme 3 hydroxy 3 methyl glutaryl coenzyme A reductase HMG CoA reductase and reduces cholesterol synthesis up to 50 at therapeutic doses This results in compensatory increase in low density lipoprotein LDL receptor expression in liver which ultimately leads to increased receptor mediated uptake and catabolism of intermediate density lipoprotein IDL and low density lipoprotein LDL It causes dose dependent lowering of LDL cholesterol and reduces hepatic synthesis of very low density lipoprotein VLDL and lowers plasma triglyceride levels It also increases high density lipoprotein HDL levels It also exerts antioxidant property

Stator 10 Tablet 15 s may cause a breakdown of skeletal muscle tissue leading to kidney failure This condition usually occurs in the elderly people with kidney disease and poorly controlled hypothyroidism underActive thyroid Stator 10 Tablet 15 s should not be prescribed to children less than 10 years of age You should contact a doctor before if you have had an allergic reaction to Stator 10 Tablet 15 s have liver problem jaundice liver cirrohosis or kidney problems pregnant or planning to get pregnant breastfeeding have severe lung disease have a previous heart attack or stroke caused by bleeding in the brain have hypothyroidism drink more than 2 servings of alcohol per day and have a muscle disorder fibromyalgia and damaged muscle tissue rhabdomyolysis