Uses / Indications:
Ramihart-H 2.5 Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
High blood pressure
Heart failure
Blood pressure
Fluid retention
Liver failure
Kidney failure
Kidney disorder
Interactions / Warnings:
RAMIHART H 2.5MG TABLET should not be given to the people allergic to RAMIHART H 2.5MG TABLET, have low blood pressure (less than 90 mm of Hg), have had a heart attack, diabetes, kidney disease, liver disease, pregnant women, or planning to get pregnant and breastfeeding women. RAMIHART H 2.5MG TABLET may alter your blood sugar level, so tell your doctor about this before using RAMIHART H 2.5MG TABLET. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), and aortic stenosis (heart valve problem). RAMIHART H 2.5MG TABLET can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking RAMIHART H 2.5MG TABLET and breastfeeding. Do not consume alcohol with RAMIHART H 2.5MG TABLET as it may increase the risk of low blood pressure. Avoid potassium supplements with RAMIHART H 2.5MG TABLET as it may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking RAMIHART H 2.5MG TABLET. Drink a lot of fluids as RAMIHART H 2.5MG TABLET can cause dehydration, so to avoid unpleasant side-effects, increase the intake of fluids. RAMIHART H 2.5MG TABLET can make your skin sensitive to sunlights try to cover the skin with a cloth or wear sunscreen lotion (SPF) whenever going outdoor.
Side Effects:
Undesirable effects reported for captopril and/or ACE inhibitor include:
Blood and lymphatic disorders:
Very Rare: neutropenia/agranulocytosis, pancytopenia particularly in patients with renal dysfunction, anaemia (including aplastic and haemolytic), thrombocytopenia, lymphadenopathy, eosinophilia, auto-immune diseases and/or positive ANA-titres.
Metabolism and nutrition disorders:
Rare: Anorexia
Very Rare: Hyperkalaemia, hypoglycaemia
Psychiatric disorders:
Common: Sleep disorders.
Very Rare: Confusion, depression.
Nervous system disorders:
Common: Taste impairment, dizziness.
Rare: Drowsiness, headache and paraesthesia.
Very Rare: Cerebrovascular incidents, including stroke, and syncope.
Eye disorders:
Very Rare: Blurred vision.
Cardiac disorders:
Uncommon: Tachycardia or tachyarrhythmia, angina pectoris, palpitations.
Very Rare: Cardiac arrest, cardiogenic shock.
Vascular disorders
Uncommon: Hypotension, Raynaud syndrome, flush, pallor.
Respiratory, thoracic and mediastinal disorders:
Common: Dry, irritating (non productive) cough and dyspnoea.
Very Rare: Bronchospasm, rhinitis, allergic alveolitis / eosinophilic pneumonia.
Gastrointestinal disorders:
Common: Nausea, vomiting, gastric irritations, abdominal pain, diarrhoea, constipation, dry mouth.
Rare: Stomatitis/aphthous ulcerations.
Very Rare: Glossitis, peptic ulcer, pancreatitis.
Hepato-biliary disorders:
Very Rare: Impaired hepatic function and cholestasis. (including jaundice), hepatitis including necrosis, elevated liver enzymes and bilirubin.
Skin and subcutaneous tissue disorders:
Common: Pruritus with or without a rash, rash and alopecia.
Uncommon: Angioedema
Very Rare: Urticaria, Stevens Johnson syndrome, erythema multiforme, photosensitivity, erythroderma, pemphigoid reactions and exfoliative dermatitis.
Musculoskeletal, connective tissue and bone disorders:
Very rare: Myalgia, arthralgia.
Renal and urinary disorders:
Rare: Renal function disorders including renal failure, polyuria, oliguria, increased urine frequency.
Very Rare: Nephrotic syndrome.
Reproductive system and breast disorders:
Very Rare: Impotence, gynaecomastia.
General disorders:
Uncommon: Chest pain, fatigue, malaise.
Very Rare: Fever
Investigations:
Very Rare: Proteinuria, eosinophilia, increase of serum potassium, decrease of serum sodium, elevation of BUN, serum creatinine and serum bilirubin, decreases in haemoglobin, haematocrit, leucocytes, thrombocytes, positive ANAtitre, elevated ESR.
Intestinal angioedema has also been reported very rarely in patients with ACE inhibitors and should be included in the differential diagnosis of patients on ACE inhibitors presenting with abdominal pain.
Medicine interaction:
RAMIHART H 2.5MG TABLET may interact with other diuretics, blood pressure-lowering drugs (aliskiren, metoprolol, sacubitril, sacuatorvastatin), anti-epilepsy medicines (carbamazepine, phenobarbital), anti-depression medicines (lithium), immune-suppressing drugs (cyclosporine), anti-diabetic drugs (metformin) and painkillers (ibuprofen, aspirin), anti-gout drugs (allopurinol), pain killers (diclofenac, ibuprofen), potassium supplements, birth control pills (drospirenone), immune system affecting drugs (everolimus, sirolimus) etc. If you are taking any of the above, speak with your doctor.