Aldactone Plus 25mg/20mg Tablet is a combination of two medicines used to reduce excess fluid levels in the body while maintaining the potassium balance. It is used to treat edema (fluid overload) and some cases of hypertension. It is best to take Aldactone Plus 25mg/20mg Tablet in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time everyday. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.