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What is Tacrolimus ointment?

Tacrolimus ointment is a topical drug that is used to treat atopic dermatitis which is a chronic skin disease causing cracks, itchiness, redness, inflammation, or scaling. When the immune system gets activated for no reason, it causes inflammation. Tacrolimus ointment inhibits the calcineurin enzyme that suppresses the immune system. The product is manufactured by GLENMARK and is also known as Tacroz forte ointment and is a substitute for immune suppressant tablets.

Benefits of Tacrolimus ointment

Tacrolimus ointment is treated with moderate to severe atopic dermatitis (eczema) in adults. It is helpful to patients who are intolerant and sensitive to traditional therapies. The ointment also helps in minimizing the frequent flares of atopic dermatitis.

How does Tacrolimus ointment work?

The active substance present in the Tacrolimus ointment, tacrolimus monohydrate acts as an immunomodulating agent. When the immune system of the skin overacts, it causes inflammation, itching, dryness, redness, etc. The ointment normalizes the immune response system that relieves the patient from skin inflammation and itching. For better results, Tacrolimus ointment is applied twice daily to the affected areas of the skin.

In the case of adults, the 0.1% concentration of tacrolimus ointment is approved, whereas, for children, 0.03% concentration is approved for the treatment. If the patient does not feel any improvement even after 6 months of application, the healthcare practitioner suggests re-examination. The application of Tacrolimus ointment for a longer duration should be avoided.


Side effects of Tacrolimus ointment

Among the skin reactions, the other side effects of tacrolimus ointment include:

  • Itching
  • Headache
  • Redness
  • Burning sensation
  • Rash
  • Fever/flu

 In rarest of the cases, it has been observed that the long-term usage of the ointment has resulted in skin cancer and lymphoma

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